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Table 5 Effects of sub-chronic oral administration of ICR on the lipid profile of females rats

From: A botanical from the antiproliferative Cameroonian spice, Imperata cylindrica is safe at lower doses, as demonstrated by oral acute and sub-chronic toxicity screenings

Females ICR (mg/kg b.w.)
Control 250 500 1000
TC (mmol/L) 1.158 ± 0.173 1.699 ± 0.161 ns 1.521 ± 0.172 ns 1.337 ± 0.167 ns
TG (mmol/L) 1.059 ± 0.141 0.843 ± 0.100 ns 1.289 ± 0.175 ns 0.994 ± 0.141 ns
HDL (mmol/L) 0.946 ± 0.129 0.883 ± 0.072 ns 0.809 ± 0.077 ns 0.965 ± 0.070 ns
LDL (mmol/L) 0.430 ± 0.023 0.442 ± 0.025ns 0.399 ± 0.0009 ns 0.378 ± 0.045 ns
  1. Results were expressed as Mean ± SEM for n = 5 animals per group. *:Significantly different from the control at p < 0.05; TC: Total cholesterol; TG: Total triglyceride; HDL: High density lipoprotein; LDL: Low density lipoprotein; ns: non significative; ICR: methanol extract of the roots of Imperata cylindrica