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Table 2 Effects of sub-chronic oral administration of ICR on relative organ weights of males rats

From: A botanical from the antiproliferative Cameroonian spice, Imperata cylindrica is safe at lower doses, as demonstrated by oral acute and sub-chronic toxicity screenings

Males ICR (mg/kg b.w.)
Control 2,505,001,000
Liver 3.117 ± 0.224 3.244 ± 0.314 ns 3.173 ± 0.138 ns 3.485 ± 0.098 ns
Heart 0.283 ± 0.008 0.293 ± 0.022 ns 0.311 ± 0.013 ns 0.333 ± 0.016*
Lungs 0.595 ± 0.056 0.650 ± 0.015 ns 0.566 ± 0.030 ns 0.656 ± 0.059 ns
Spleen 0.355 ± 0.031 0.325 ± 0.010ns 0.392 ± 0.049 ns 0.338 ± 0.013 ns
Kidney 0.604 ± 0.003 0.618 ± 0.020 ns 0.657 ± 0.020* 0.654 ± 0.023*
  1. Results were expressed as Mean ± SEM for n = 5 animals per group. *:Significantly different from the control at p < 0.05; ns: non significative; ICR: methanol extract of the roots of Imperata cylindrica