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Table 2 Effects of sub-chronic oral administration of ICR on relative organ weights of males rats

From: A botanical from the antiproliferative Cameroonian spice, Imperata cylindrica is safe at lower doses, as demonstrated by oral acute and sub-chronic toxicity screenings

Males

ICR (mg/kg b.w.)

Control 2,505,001,000

Liver

3.117 ± 0.224

3.244 ± 0.314 ns

3.173 ± 0.138 ns

3.485 ± 0.098 ns

Heart

0.283 ± 0.008

0.293 ± 0.022 ns

0.311 ± 0.013 ns

0.333 ± 0.016*

Lungs

0.595 ± 0.056

0.650 ± 0.015 ns

0.566 ± 0.030 ns

0.656 ± 0.059 ns

Spleen

0.355 ± 0.031

0.325 ± 0.010ns

0.392 ± 0.049 ns

0.338 ± 0.013 ns

Kidney

0.604 ± 0.003

0.618 ± 0.020 ns

0.657 ± 0.020*

0.654 ± 0.023*

  1. Results were expressed as Mean ± SEM for n = 5 animals per group. *:Significantly different from the control at p < 0.05; ns: non significative; ICR: methanol extract of the roots of Imperata cylindrica