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Table 1 Effects of sub-chronic oral administration of ICR on relative organs weights of females rats

From: A botanical from the antiproliferative Cameroonian spice, Imperata cylindrica is safe at lower doses, as demonstrated by oral acute and sub-chronic toxicity screenings

Females ICR (mg/kg b.w.)
Control 250 500 1000
Liver 3.442 ± 0.348 3.510 ± 0.350 ns 3.562 ± 0.167 ns 3.638 ± 0.247 ns
Heart 0.333 ± 0.017 0.291 ± 0.001 ns 0.314 ± 0.017 ns 0.328 ± 0.025 ns
Lungs 0.630 ± 0.094 0.652 ± 0.024 ns 0.646 ± 0.086 ns 0.701 ± 0.123 ns
Spleen 0.405 ± 0.103 0.364 ± 0.024 ns 0.362 ± 0.023 ns 0.365 ± 0.003 ns
Kidney 0.650 ± 0.007 0.646 ± 0.033 ns 0.649 ± 0.034 ns 0.646 ± 0.015 ns
  1. Results were expressed as Mean ± SEM for n = 5 animals per group. Significantly different from the control at p < 0.05; ns: non significative; ICR: methanol extract of the roots of Imperata cylindrica