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Table 1 Effects of sub-chronic oral administration of ICR on relative organs weights of females rats

From: A botanical from the antiproliferative Cameroonian spice, Imperata cylindrica is safe at lower doses, as demonstrated by oral acute and sub-chronic toxicity screenings

Females

ICR (mg/kg b.w.)

Control

250

500

1000

Liver

3.442 ± 0.348

3.510 ± 0.350 ns

3.562 ± 0.167 ns

3.638 ± 0.247 ns

Heart

0.333 ± 0.017

0.291 ± 0.001 ns

0.314 ± 0.017 ns

0.328 ± 0.025 ns

Lungs

0.630 ± 0.094

0.652 ± 0.024 ns

0.646 ± 0.086 ns

0.701 ± 0.123 ns

Spleen

0.405 ± 0.103

0.364 ± 0.024 ns

0.362 ± 0.023 ns

0.365 ± 0.003 ns

Kidney

0.650 ± 0.007

0.646 ± 0.033 ns

0.649 ± 0.034 ns

0.646 ± 0.015 ns

  1. Results were expressed as Mean ± SEM for n = 5 animals per group. Significantly different from the control at p < 0.05; ns: non significative; ICR: methanol extract of the roots of Imperata cylindrica