Evaluation of the antimicrobial activity and safety of Rhus vulgaris (Anacardiaceae) extracts

Table 3 Weights of Mice used in Acute Toxicity assay for Day 1, 7 and 14

Plant extracts	Concentration	Cage	Day 1	Day 7	Day 14	Mean±	Standard	Significance
	(mg/kg)						Deviation	Control 1	Control 2	Control 3
Control 1	DH₂O	C 1^a	20	20	22	20.6667	1.15470	NA	0.356	1.000
Control 2	DH₂O	C 2^b	24	25	26	25.0000	1.00000	0.356	NA	0.983
Control 3	DH₂O	C 3^c	20	22	25	22.3333	2.51661	1.000	0.983	NA
R. vulgaris	50	R.v. 1^a	22	22	24	22.6667	1.15470	1.000	0.997	1.000
R. vulgaris	50	R.v. 1^b	22	22	23	22.3333	0.57735	1.000	0.983	1.000
R. vulgaris	50	R.v. 1^c	25	25	26	25.3333	0.57735	0.225	1.000	0.936
R. vulgaris	300	R.v. 2^a	24	25	26	25.0000	1.00000	0.356	1.000	0.983
R. vulgaris	300	R.v. 2^b	24	22	25	23.6667	1.52753	0.936	1.000	1.000
R. vulgaris	300	R.v. 2^c	22	23	24	23.0000	1.00000	0.997	1.000	1.000
R. vulgaris	2000	R.v. 3^a	21	23	25	23.0000	2.00000	0.997	1.000	1.000
R. vulgaris	2000	R.v. 3^b	24	25	28	25.6667	2.08167	0.132	1.000	0.838
R. vulgaris	2000	R.v. 3^c	21	22	24	22.3333	1.52753	1.000	0.983	1.000

There were four cages. One cage had the control group while the other three had the test groups. Each cage had 3 mice. All the mice in one cage received the same concentration of control/plant extract. R. vulgaris: Rhus vulgaris, DH₂O: Distilled water, C 1: Control 1, C 2: Control 2, C 3: Control 3, ^a: Mouse No.1, ^b: Mouse No. 2, ^c: Mouse No. 3, R.v. 1 ^a: Oral dose of Rhus vulgaris (50 mg/kg) administered to Mouse No. 1, R.v. 1^b: Oral dose of R. vulgaris (50 mg/kg) administered to Mouse No. 2, R.v. 1^c: Oral dose of R. vulgaris (50 mg/kg) administered to Mouse No. 3, R.v. 2^a: Oral dose of R. vulgaris (300 mg/kg) administered to Mouse No. 1, R.v. 2^b: Oral dose of R. vulgaris (300 mg/kg) administered to Mouse No. 2, R.v. 2^b: Oral dose of R. vulgaris (300 mg/kg) administered to Mouse No. 2, R.v. 2^c: Oral dose of R. vulgaris (300 mg/kg) administered to Mouse No. 3, R.v. 3^a: Oral dose of R. vulgaris (2000 mg/kg) administered to Mouse No. 1, R.v. 3^b: Oral dose of R. vulgaris (2000 mg/kg) administered to Mouse No. 2, R.v. 3^c: Oral dose of R. vulgaris (2000 mg/kg) administered to Mouse No. 1, NA: Not applicable

ISSN: 2662-7671