Fig. 3

Ginger extract inhibited NF-κB activation and proinflammatory gene expression in IBS-D rats CECs. a. Western blot showed ginger extract inhibited NF-κB activation in IBS-D rats CECs (up panel). The relative density of IκBα/β-actin, p-p65/p65 were also showed (down panel). b. RT-qPCR showed ginger extract inhibited proinflammatory gene expression in IBS-D rats CECs. ^#P < 0.05 indicates significant differences between IBS-D rats model group and ginger groups (10, 50, 100 and 200 μg/mL). *P < 0.05 indicates significant differences between ginger groups (10, 50, 100 and 200 μg/mL)