Skip to main content
Fig. 6 | BMC Complementary Medicine and Therapies

Fig. 6

From: Anti-inflammation effects of the total saponin fraction from Dioscorea nipponica Makino on rats with gouty arthritis by influencing MAPK signalling pathway

Fig. 6

Immunohistochemical staining of MKK4, p-MKK, ICAM1 and VCAM1 in rat synovium tissue. (A) Control group and (B) model group were treated with saline for 5 days. (C) High dose group (D) middle dose group and (E) Low group were treated with extract of RDN for 5 days, and dose amounted to 40 mg/kg, 80 mg/kg and 160 mg/kg daily, respectively. Each slide was examined at a magnification of 200 times and purple MKK4, p-MKK, ICAM1 and VCAM1 positive cell can be found within rat synovium tissue. Images shown are a representative from three independent trials. #p < 0.5 vs control group (independent samples t-test), *p < 0.05 vs model group (one-way ANOVA followed by Dunnett’s t-test)

Back to article page