Skip to main content
Fig. 4 | BMC Complementary Medicine and Therapies

Fig. 4

From: Anti-inflammation effects of the total saponin fraction from Dioscorea nipponica Makino on rats with gouty arthritis by influencing MAPK signalling pathway

Fig. 4

Immunohistochemical staining of ERK1/2, p-ERK1/2, MEK and p-MEK in rat synovium tissue. (A) Control group and (B) model group were treated with saline for 5 days. (C) High dose group (D) middle dose group and (E) Low group were treated with extract of RDN for 5 days, and dose amounted to 40 mg/kg, 80 mg/kg and 160 mg/kg daily, respectively. Each slide was examined at a magnification of 200 times and purple ERK1/2, p-ERK1/2, MEK and p-MEK positive cell can be found within rat synovium tissue. Images shown are a representative from three independent trials. ##p < 0.01 vs control group (independent samples t-test), *p < 0.05 vs model group; **p < 0.01 vs model group (one-way ANOVA followed by Dunnett’s t-test)

Back to article page
\