Table 1 Characterization and details information in 52 safflower compounds and 48 salvia compounds. OB: oral bioavailability. DL: drug-like

HH-01

Syrigin

14.64

0.32

DS-01

1,2,5,6-tetrahydrotanshinone

38.75

0.36

HH-02

Pyrethrin II

48.36

0.35

DS-02

Poriferasterol

43.83

0.76

HH-03

VIV

14.26

0.55

DS-03

Poriferast-5-en-3beta-ol

36.91

0.75

HH-04

Gamma-Tocotrienol

20.3

0.53

DS-04

Sugiol

36.11

0.28

HH-05

Rutin

3.2

0.68

DS-05

Dehydrotanshinone II A

43.76

0.4

HH-06

6-hydroxykaempferol-3-O-beta-D-glucoside

1.85

0.76

DS-06

Baicalin

40.12

0.75

HH-07

β-amyrin acetate

9.11

0.74

DS-07

Digallate

61.85

0.26

HH-08

Nicotiflorin

3.64

0.73

DS-08

Luteolin

36.16

0.25

HH-09

(+)-Syringaresinol

3.29

0.72

DS-09

5,6-dihydroxy-7-isopropyl-1,1-dimethyl-2,3-dihydrophenanthren-4-one

33.77

0.29

HH-10

Baicalin

40.12

0.75

DS-10

2-isopropyl-8-methylphenanthrene-3,4-dione

40.86

0.23

HH-11

6-Hydroxykaempferol

62.13

0.27

DS-11

3α-hydroxytanshinoneIIa

44.93

0.44

HH-12

Sitogluside

20.63

0.62

DS-12

(E)-3-[2-(3,4-dihydroxyphenyl)-7-hydroxy-benzofuran-4-yl]acrylic acid

48.24

0.31

HH-13

Astragalin

14.03

0.74

DS-13

4-methylenemiltirone

34.35

0.23

HH-14

Baicalein

33.52

0.21

DS-14

2-(4-hydroxy-3-methoxyphenyl)-5-(3-hydroxypropyl)-7-methoxy-3-benzofurancarboxaldehyde

62.78

0.4

HH-15

Luteolin

36.16

0.25

DS-15

Formyltanshinone

73.44

0.42

HH-16

Arachic acid

16.66

0.19

DS-16

3-beta-Hydroxymethyllenetanshiquinone

32.16

0.41

HH-17

Kaempferol

41.88

0.24

DS-17

Methylenetanshinquinone

37.07

0.36

HH-18

Apigenin

23.06

0.21

DS-18

Przewaquinone B

62.24

0.41

HH-19

Myricetin

13.75

0.21

DS-19

Przewaquinone c

55.74

0.4

HH-20

Scutellarein

18.97

0.24

DS-20

(6S,7R)-6,7-dihydroxy-1,6-dimethyl-8,9-dihydro-7H-naphtho [8,7-g] benzofuran-10,11-dione

41.31

0.45

HH-21

Lupeol

12.12

0.78

DS-21

Przewaquinone f

40.31

0.46

HH-22

Lignan

43.32

0.65

DS-22

Sclareol

43.67

0.21

HH-23

Nonacosanol

10.57

0.43

DS-23

Tanshinaldehyde

52.47

0.45

HH-24

Thymopentin

1.24

0.46

DS-24

Danshenol B

57.95

0.56

HH-25

Beta-carotene

37.18

0.58

DS-25

Danshenol A

56.97

0.52

HH-26

Quercetin

46.43

0.28

DS-26

Salvilenone

30.38

0.38

HH-27

ADO

15.98

0.18

DS-27

Cryptotanshinone

52.34

0.4

HH-28

Fluoranthene

24.7

0.18

DS-28

Dan-shexinkum d

38.88

0.55

HH-29

CLR

37.87

0.68

DS-29

Danshenspiroketallactone

50.43

0.31

HH-30

Poriferast-5-en-3beta-ol

36.91

0.75

DS-30

Deoxyneocryptotanshinone

49.4

0.29

HH-31

Beta-sitosterol

36.91

0.75

DS-31

Dihydrotanshinlactone

38.68

0.32

HH-32

Stigmasterol

43.83

0.76

DS-32

DihydrotanshinoneI

45.04

0.36

HH-33

Vitamin-G

6.79

0.50

DS-33

Isocryptotanshi-none

54.98

0.39

HH-34

Carthamone

5.93

0.63

DS-34

Isotanshinone II

49.92

0.4

HH-35

Quercetagetin

45.01

0.31

DS-35

Manool

45.04

0.2

HH-36

Hydroxysafflor-yellow-A

4.77

0.68

DS-36

Miltionone I

49.68

0.32

HH-37

Amoenin A3

3.32

0.74

DS-37

Miltirone

38.76

0.25

HH-38

Sesquiterpene

5.86

0.67

DS-38

Neocryptotanshinone II

39.46

0.23

HH-39

6-hydroxykaempferol-3-O-glucoside

1.97

0.76

DS-39

Neocryptotanshinone

52.49

0.32

HH-40

7,8-dimethyl-1H-pyrimido[5,6-g]quinoxaline-2,4-dione

45.75

0.19

DS-40

1-methyl-8,9-dihydro-7H-naphtho [5,6-g] benzofuran-6,10,11-trione

34.72

0.37

HH-41

5,8-dimethyltocol

15.62

0.52

DS-41

Prolithospermic acid

64.37

0.31

HH-42

6-hydroxykaempferol-3,6-di-O-beta-D-glucoside

4.21

0.68

DS-42

Salvianolic acid j

43.38

0.72

HH-43

Tagetiin

28.34

0.78

DS-43

(6S)-6-hydroxy-1-methyl-6-methylol-8,9-dihydro-7H-naphtho[8,7-g]benzofuran-10,11-quinone

75.39

0.46

HH-44

Sophoraflavonoloside

5.3

0.71

DS-44

Tanshindiol B

42.67

0.45

HH-45

Quercetin-3,7-di-O-beta-d-glucoside

5.86

0.67

DS-45

Przewaquinone E

42.85

0.45

HH-46

Lirioresinol-A

1.76

0.67

DS-46

Tanshinone IIA

49.89

0.4

HH-47

Precarthamin

22

0.67

DS-47

(6S)-6-(hydroxymethyl)-1,6-dimethyl-8,9-dihydro-7H-naphtho[8,7-g]benzofuran-10,11-dione

65.26

0.45

HH-48

Carthamone

5.93

0.63

DS-48

Tanshinone VI

45.64

0.3

HH-49

Octacosane

8.15

0.37

HH-51

Safflomin-C

5.57

0.66

HH-50

Safflomin-A

3.53

0.68

HH-52

Safflow-yellow-A

27.16

0.70