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Table 2 Minimum inhibitory concentrations of combined fractions obtained from silica gel column against most susceptible strains in mg/mL

From: Flavonoids isolated from the South African weed Chromolaena odorata (Asteraceae) have pharmacological activity against uropathogens

Organism

Time (h)

Sub-Fraction

   
 

F1

F2

F3

F4

F5

F6

S. aureus

–

> 2.5

0.08*

0.16

0.16

0.3

0.31

K. pneumoniae

–

1.25

0.3

0.16

0.63

0.313

0.16

E. coli (1)

–

0.63

0.16

0.16

0.63

0.63

0.63

E. faecalis

–

1.25

0.31

0.31

2.5

2.5

0.63

C. albicans

48

2.5

> 2.5

2.5

2.5

2.5

2.5

 

72

> 2.5

> 2.5

> 2.5

> 2.5

> 2.5

> 2.5

A. fumigatus

48

1.25

0.16

0.08*

0.63

1.25

0.31

 

72

> 2.5

0.63

0.63

> 2.5

> 2.5

> 2.5

 

120

> 2.5

> 2.5

> 2.5

> 2.5

> 2.5

> 2.5

C. neoformans

48

> 2.5

0.31

0.31

0.31

0.16

0.31

 

72

> 2.5

0.63

1.25

2.5

2.5

> 2.5

  1. F1 fraction 1, F2 fraction 2, F3 fraction 3, F4 fraction 4, F5 fraction 5, F6 fraction 6. Values with bold indicate promising antimicrobial activity while value in asterisk indicate best activity