Table 2 Information for top 10 pathways

1

PI3K-Akt signaling pathway

AKT1, EGF, IL6, INS, MAPK1, MAPK3, TP53, VEGFA

2.25E-07

2

HIF-1 signaling pathway

AKT1, EGF, IL6, INS, MAPK1, MAPK3, STAT3, VEGFA

8.24E-16

3

TNF signaling pathway

AKT1, CASP3, IL1B, IL6, JUN, MAPK1, MAPK3, MMP9, PTGS2, TNF

7.25E-15

4

Toll-like receptor signaling pathway

AKT1, CXCL8, IL1B, IL6, JUN, MAPK1, MAPK3, TNF

1.23E-12

5

FoxO signaling pathway

AKT1, EGF, IL10, IL6, INS, MAPK1, MAPK3, STAT3

5.82E-10

6

T cell receptor signaling pathway

AKT1, IL10, JUN, MAPK1, MAPK3, TNF

8.99E-08

7

NF-κB signaling pathway

CXCL8, IL1B, PTGS2, TNF

1.85E-07

8

NOD-like receptor signaling pathway

CXCL8, IL1B, IL6, MAPK1, MAPK3, TNF

2.33E-08

9

Apoptosis

CASP3, TNF, TP53, AKT1

6.48E-08

10

Prolactin signaling pathway

AKT1, INS, MAPK1, MAPK3, STAT3

2.45E-07