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Table 1 Effect of CEE on the levels of TNF-α and IL-6 in ALI mice

From: Protective effect of Chrysanthemum morifolium Ramat. ethanol extract on lipopolysaccharide induced acute lung injury in mice

Group

Dose

3 h after molding

TNF-α (ng/g)

IL-6 (ng/g)

Normal

363.35 ± 41.80

60.06 ± 5.93

Model

539.5 ± 20.4##

101.31 ± 13.65##

CEE-low

50 mg/kg

482.75 ± 41.98**

95.62 ± 9.17*

CEE-medium

100 mg/kg

444.83 ± 12.11**

90.10 ± 5.11**

CEE-high

200 mg/kg

437.55 ± 12.12**

80.00 ± 8.74**

  

6 h after molding

Normal

363.42 ± 31.12

59.35 ± 5.47

Model

511.45 ± 31.9##

112.63 ± 5.01##

CEE-low

50 mg/kg

462.60 ± 18.11*

79.89 ± 10.12

CEE-medium

100 mg/kg

416.32 ± 19.62*

71.18 ± 4.76*

CEE-high

200 mg/kg

407.35 ± 4.99**

65.78 ± 9.20**

  

24 h after molding

Normal

362.49 ± 30.43

60.21 ± 4.86

Model

500.5 ± 20.4##

106.78 ± 9.13##

CEE-low

50 mg/kg

419.33 ± 8.92**

75.34 ± 13.53*

CEE-medium

100 mg/kg

392.00 ± 21.38**

65.39 ± 9.23**

CEE-high

200 mg/kg

380.05 ± 12.43**

62.41 ± 10.27**

  1. Data are present as mean ± SD (n = 18). ##P < 0.01 vs normal group, *P < 0.05, **P < 0.01 vs model group. CEE: Chrysanthemum morifolium Ramat. ethanol extract; ALI: acute lung injury