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Fig. 6 | BMC Complementary Medicine and Therapies

Fig. 6

From: Curcumin inhibits the migration of osteoclast precursors and osteoclastogenesis by repressing CCL3 production

Fig. 6

The current working model regarding curcumin-inhibited OCP migration during the osteoclastogenesis. CCL3 promote the recruitment of OCPs by binding to CCR1 on OCPs, which leads to the fusion and differentiation of osteoclasts. Curcumin inhibits the migration of OCPs and osteoclastogenesis by repressing the production of CCL3 in OCPs. OC, osteoclast; OCP, osteoclast precursor

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