Table 2 Comparison of lipid profile through the study period (baseline till week-26)
From: Repeatedly heated mix vegetable oils-induced atherosclerosis and effects of Murraya koenigii
Observation Time | Control | RHMVO | Mk LE-300 | Mk LE-500 | Lovastatin |
|---|---|---|---|---|---|
TRIG (mg/dl) | |||||
week 1-baseline (Before induction) | 56.32 ± 3.51 | 55.43 ± 2.21 | 55.62 ± 3.28 | 57.08 ± 3.80 | 56.58 ± 3.18 |
week 16 (Post induction) | 69.08 ± 2.92 | 272.18 ± 1.76** | 279.61 ± 6.76** | 281.4 ± 6.03** | 276.01 ± 12.31** |
week 20 | 73.17 ± 2.11 | 309.26 ± 1.83** | 251.83 ± 6.16 | 256.01 ± 6.19 | 255.67 ± 12.05 |
week 23 | 74.75 ± 3.42 | 330.61 ± 1.55** | 220.05 ± 6.28 | 218.76 ± 5.05 | 224.46 ± 12.92 |
week 26 | 75.93 ± 4.0 | 352.07 ± 6.74** | 179.06 ± 6.09 # | 166.51 ± 3.08 ## | 195.2 ± 12.41# |
TC (mg/dl) | |||||
week 1- baseline (Before induction) | 141.02 ± 3.21 | 140.12 ± 3.25 | 141.21 ± 5.02 | 141.30 ± 3.55 | 141.25 ± 1.58 |
week 16 (Post induction) | 148.54 ± 4.25 | 444.5 ± 8.23** | 446.31 ± 8.59** | 450.35 ± 8.91** | 443.29 ± 11.61** |
week 20 | 150.19 ± 5.23 | 503.45 ± 8.09** | 394.07 ± 8.23 | 378.1 ± 8.09 | 388.08 ± 11.06 |
week 23 | 151.84 ± 3.02 | 562.4 ± 8.55** | 350.75 ± 7.99 | 289.85 ± 8.23# | 333.82 ± 11.31 |
week 26 | 154.4 ± 3.87 | 637.75 ± 9.99** | 308.51 ± 8.32# | 200.59 ± 8.59## | 280.61 ± 11.38## |
LDL (mg/dl) | |||||
week 1- baseline (Before induction) | 48.23 ± 3.29 | 47.22 ± 1.29 | 48.01 ± 3.31 | 47.59 ± 3.98 | 47.29 ± 3.19 |
week 16 (Post induction) | 67.66 ± 3.31 | 367.61 ± 15.22** | 366.21 ± 18.30** | 363.57 ± 14.69** | 361.63 ± 14.17** |
week 20 | 68.87 ± 3.06 | 405.59 ± 18.23** | 351.9 ± 15.09 | 326.36 ± 14.09 | 326.62 ± 14.29 |
week 23 | 69.72 ± 3.25 | 439.84 ± 10.59** | 333.59 ± 11.66 | 271.24 ± 11.05 | 278.36 ± 10.09 |
week 26 | 73.92 ± 2.88 | 481.22 ± 75.05** | 311.35 ± 18.36 | 213.59 ± 10.29## | 240.65 ± 12.07# |
VLDL (mg/dl) | |||||
week 1- baseline (Before induction) | 11.08 ± 0.56 | 11.22 ± 0.77 | 11.21 ± 0.81 | 11.10 ± 0.67 | 11.02 ± 0.66 |
week 16 (Post induction) | 14.88 ± 0.74 | 82.18 ± 3.97** | 82.73 ± 4.49** | 84.27 ± 4.29** | 82.55 ± 3.89** |
week 20 | 15.84 ± 0.70 | 90.43 ± 3.29** | 77.52 ± 4.20 | 73.06 ± 5.20 | 72.38 ± 3.34 |
week 23 | 16.65 ± 0.62 | 98.68 ± 5.02** | 70.31 ± 4.35 | 55.85 ± 4.35# | 60.49 ± 3.09 |
week 26 | 16.52 ± 0.53 | 105.55 ± 3.07** | 62.2 ± 2.21 | 30.64 ± 4.04## | 48.51 ± 4.52# |
HDL (mg/dl) | |||||
week 1- baseline (Before induction) | 53.23 ± 8.69 | 53.33 ± 7.05 | 53.53 ± 6.05 | 54.59 ± 6.29 | 53.09 ± 8.34 |
week 16 (Post induction) | 69.64 ± 3.35 | 16.08 ± 1.67$$ | 15.78 ± 2.17$$ | 15.03 ± 2.22$$ | 15.03 ± 2.19$$ |
week 20 | 70.92 ± 6.09 | 13 ± 1.38$$ | 21.99 ± 2.01 | 32.18 ± 2.56^ | 24.28 ± 2.65 |
week 23 | 71.18 ± 2.95 | 9.32 ± 2.08$$ | 40.08 ± 3.55^ | 67.43 ± 4.05^^ | 34.63 ± 5.29^ |
week 26 | 73.92 ± 5.01 | 5.64 ± 2.59$$ | 58.06 ± 3.23^ | 81.68 ± 2.92^^ % | 42.89 ± 4.84^ |