Table 1 Information of 36 hub targets
Uniprot ID | Gene Symbol | Description |
|---|---|---|
P15692 | VEGFA | vascular endothelial growth factor A |
P04637 | TP53 | tumor protein p53 |
P01133 | EGF | epidermal growth factor |
P00533 | EGFR | epidermal growth factor receptor |
P35354 | PTGS2 | prostaglandin-endoperoxide synthase 2 |
P14780 | MMP9 | matrix metallopeptidase 9 |
P05412 | JUN | Jun proto-oncogene, AP-1 transcription factor subunit |
P45983 | MAPK8 | mitogen-activated protein kinase 8 |
P01584 | IL1B | interleukin 1 beta |
P03372 | ESR1 | estrogen receptor 1 |
P04040 | CAT | catalase |
P07900 | HSP90AA1 | heat shock protein 90 alpha family class A member 1 |
P29474 | NOS3 | nitric oxide synthase 3 |
P08253 | MMP2 | matrix metallopeptidase 2 |
P37231 | PPARG | peroxisome proliferator activated receptor gamma |
P05067 | APP | amyloid beta precursor protein |
P42345 | MTOR | mechanistic target of rapamycin kinase |
Q16539 | MAPK14 | mitogen-activated protein kinase 14 |
P04150 | NR3C1 | nuclear receptor subfamily 3 group C member 1 |
P05164 | MPO | myeloperoxidase |
Q07817 | BCL2L1 | BCL2 like 1 |
P10275 | AR | androgen receptor |
P60568 | IL2 | interleukin 2 |
P35968 | KDR | kinase insert domain receptor |
P19320 | VCAM1 | vascular cell adhesion molecule 1 |
P00441 | SOD1 | superoxide dismutase 1 |
P08684 | CYP3A4 | cytochrome P450 family 3 subfamily A member 4 |
P01579 | IFNG | interferon gamma |
Q16665 | HIF1A | hypoxia inducible factor 1 subunit alpha |
P19838 | NFKB1 | nuclear factor kappa B subunit 1 |
P00734 | F2 | coagulation factor II, thrombin |
Q02750 | MAP 2 K1 | mitogen-activated protein kinase kinase 1 |
P06401 | PGR | progesterone receptor |
O60674 | JAK2 | Janus kinase 2 |
P21964 | COMT | catechol-O-methyltransferase |
P03956 | MMP1 | matrix metallopeptidase 1 |