Fig. 6From: Matrine inhibits the growth of natural killer/T-cell lymphoma cells by modulating CaMKIIγ-c-Myc signaling pathwayCartoon diagram of the mechanisms for growth suppression of NKTCL cells by matrine. Matrine inhibits the transcription of c-Myc through the downregulated LMP1 protein. Matrine downregulates c-Myc phosphorylation at Ser62 through CaMKIIγ inhibition, and then promotes the destabilization and degradation of c-Myc protein in a proteasome-dependent mannerBack to article page