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Fig. 5 | BMC Complementary Medicine and Therapies

Fig. 5

From: Matrine inhibits the growth of natural killer/T-cell lymphoma cells by modulating CaMKIIγ-c-Myc signaling pathway

Fig. 5

Matrine inhibited NKTCL cells through CaMKIIγ/c-Myc pathway. a NK92 cells were treated with 1.96 mM matrine for 48 h, followed by western blot for c-Myc, p-c-Myc (Ser62), CaMKIIγ and LMP1 antibodies. GAPDH was used as loading control. b The relative intensities of target proteins were normalized to those of loading control (**p < 0.01). c LMP1, RUNX3, EZH2, miR-26a, miR-26b and miR-101 transcription levels in NK92 cells were determined by quantitative RT-PCR at 24 h after matrine treatment at 0, 1.2, 2.4, and 3.6 mM (*p < 0.05, **p < 0.01 compared to 0 mM group). Analyses in triplicates

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