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Table 5 Zone of inhibition for the root extract of B. antidysenterica against selected diarrhoea causing bacteria

From: Evaluation of in-vivo antidiarrhoeal and in-vitro antibacterial activities of the root extract of Brucea antidysenterica J. F. Mill (Simaroubaceae)

Extract Concentration S. flexneri (ATCC-12022)
(mm)
S. typhi (ATCC-13062)
(mm)
Salmonella Spp. (CI)
(mm)
E. coli (ATCC-25922)
(mm)
E. coli (CI)
(mm)
P. aeruginosa (ATCC-27853)
(mm)
80% BAE BAE 200 mg/mL 14.7 ± 0.33 a3d2 14.7 ± 0.33 a3c2d3 NA 14.0 ± 0.00 a3c2d3 NA 16.7 ± 0.33 a3c3d3
BAE 400 mg/mL 17.3 ± 0.67 a3d1 17.7 ± 0.33 a3b2 NA 16.7 ± 0.33 a3b1d2 NA 19.7 ± 0.33 a3b3d2
BAE 800 mg/mL 20.7 ± 0.33 a3b2c1 19.3 ± 0.33 a3b3 NA 18.3 ± 0.33 a3b1c3 NA 22.0 ± 0.00 a3b3c2
Standards Cipro 5 μg/disc 29.3 ± 1.20 34.3 ± 0.67 18.0 ± 0.00 32.3 ± 0.33 NA
Cefta 30 μg/disc 10.3 ± 0.33
  1. Data are expressed as Mean ± SEM (n = 3), a compared to positive control; b compared to 200 mg/mL; c compared to 400 mg/mL; d compared to 800 mg/mL; 1P < 0.05, 2P <0.01, 3P <0.001. The negative control has shown no antibacterial activity. The positive controls: BAE Brucea antidysenterica extract, Cipro Ciprofloxacin, Cefta Ceftazidime, NA No Activity