Skip to main content

Table 5 Zone of inhibition for the root extract of B. antidysenterica against selected diarrhoea causing bacteria

From: Evaluation of in-vivo antidiarrhoeal and in-vitro antibacterial activities of the root extract of Brucea antidysenterica J. F. Mill (Simaroubaceae)

Extract

Concentration

S. flexneri (ATCC-12022)

(mm)

S. typhi (ATCC-13062)

(mm)

Salmonella Spp. (CI)

(mm)

E. coli (ATCC-25922)

(mm)

E. coli (CI)

(mm)

P. aeruginosa (ATCC-27853)

(mm)

80% BAE

BAE 200 mg/mL

14.7 ± 0.33 a3d2

14.7 ± 0.33 a3c2d3

NA

14.0 ± 0.00 a3c2d3

NA

16.7 ± 0.33 a3c3d3

BAE 400 mg/mL

17.3 ± 0.67 a3d1

17.7 ± 0.33 a3b2

NA

16.7 ± 0.33 a3b1d2

NA

19.7 ± 0.33 a3b3d2

BAE 800 mg/mL

20.7 ± 0.33 a3b2c1

19.3 ± 0.33 a3b3

NA

18.3 ± 0.33 a3b1c3

NA

22.0 ± 0.00 a3b3c2

Standards

Cipro 5 μg/disc

29.3 ± 1.20

34.3 ± 0.67

18.0 ± 0.00

32.3 ± 0.33

NA

Cefta 30 μg/disc

10.3 ± 0.33

  1. Data are expressed as Mean ± SEM (n = 3), a compared to positive control; b compared to 200 mg/mL; c compared to 400 mg/mL; d compared to 800 mg/mL; 1P < 0.05, 2P <0.01, 3P <0.001. The negative control has shown no antibacterial activity. The positive controls: BAE Brucea antidysenterica extract, Cipro Ciprofloxacin, Cefta Ceftazidime, NA No Activity