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Table 4 In vivo antidiarrhoeal index of the root extract of B. antidysenterica

From: Evaluation of in-vivo antidiarrhoeal and in-vitro antibacterial activities of the root extract of Brucea antidysenterica J. F. Mill (Simaroubaceae)

Extract Dose Administered Delay in defecation time (Dfreq)
(%)
Gut meal travel distance (Gmeq) (%) Purging frequency in number of wet stools (%) In vivo Anti-diarrhoeal Index (ADI)
80% BAE DW 10 mL/kg
Loperamide 3 mg/kg 118.37 67.35 82.22 83.07
BAE 100 mg/kg 17.50 39.13 53.33 32.04
BAE 200 mg/kg 98.24 55.34 82.22 73.22
BAE 400 mg/kg 126.69 67.59 88.89 87.60
  1. BAE B. antidysenterica extract, DW distilled water