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Table 4 In vivo antidiarrhoeal index of the root extract of B. antidysenterica

From: Evaluation of in-vivo antidiarrhoeal and in-vitro antibacterial activities of the root extract of Brucea antidysenterica J. F. Mill (Simaroubaceae)

Extract

Dose Administered

Delay in defecation time (Dfreq)

(%)

Gut meal travel distance (Gmeq) (%)

Purging frequency in number of wet stools (%)

In vivo Anti-diarrhoeal Index (ADI)

80% BAE

DW 10 mL/kg

–

–

–

–

Loperamide 3 mg/kg

118.37

67.35

82.22

83.07

BAE 100 mg/kg

17.50

39.13

53.33

32.04

BAE 200 mg/kg

98.24

55.34

82.22

73.22

BAE 400 mg/kg

126.69

67.59

88.89

87.60

  1. BAE B. antidysenterica extract, DW distilled water