Revealing the sedative-hypnotic effect of the extracts of herb pair Semen Ziziphi spinosae and Radix Polygalae and related mechanisms through experiments and metabolomics approach

Table 4 Contents of excitatory neurotransmitters NE and DA in brain tissues of mice (n = 10, \( \overline{x} \) ±s)

Group	Dosage/mg•kg⁻¹	NE/10⁻³	DA/10⁻³
Normal group	–	10.95 ± 1.01	6.34 ± 0.67
Model group	–	18.90 ± 1.86^**	11.25 ± 2.26^**
EI30 high-dose group	13.8	15.52 ± 1.27^**	10.24 ± 1.23^**
EI30 medium-dose group	6.9	17.42 ± 0.94^**	8.20 ± 0.77^**△
EI30 low-dose group	3.45	17.75 ± 2.14^**△△	9.18 ± 1.09^**

Note: Compared with the normal group: * P < 0.05, ** P < 0.01.Compared with the model group: ^△P<0.05, ^△△P<0.01

ISSN: 2662-7671