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Table 3 Contents of neurotransmitters 5-HT and GABA in brain tissues of mice (n = 10, \( \overline{x} \) ±s)

From: Revealing the sedative-hypnotic effect of the extracts of herb pair Semen Ziziphi spinosae and Radix Polygalae and related mechanisms through experiments and metabolomics approach

Group

Dosage/mg•kg−1

5-HT/10−2

GABA/nmol•ng− 1

Normal group

–

3.91 Â± 0.73

1.22 Â± 0.24

Model group

–

2.58 Â± 0.20**

1.77 Â± 0.18**

EI30 high-dose group

13.8

3.16 Â± 0.39△△

1.52 Â± 0.18*â–³

EI30 medium-dose group

6.9

3.37 Â± 0.56△△

2.00 Â± 0.32**

EI30 low-dose group

3.45

3.70 Â± 0.62△△

2.03 Â± 0.19**â–³

  1. Note: Compared with the normal group: * P < 0.05, ** P < 0.01. Compared with the model group: △P<0.05, △△P<0.01