Revealing the sedative-hypnotic effect of the extracts of herb pair Semen Ziziphi spinosae and Radix Polygalae and related mechanisms through experiments and metabolomics approach

Table 2 Effect of EI30 on sleep latency and duration (\( \overline{x} \) ±s)

Group	Dosage/(mg·kg^− 1)	Sleep latency /min	Sleep duration/min
Control group	–	41.2 ± 19.8	2.8 ± 3.1
Clonazepam	0.01	2.78 ± 0.83**	142.5 ± 13.44**
EI30 high-dose group	13.8	4.5 ± 2.4**^##	18.7 ± 11.7**
EI30 medium-dose group	6.9	4.0 ± 1.9**^##	10.1 ± 4.5**
EI30 low-dose group	3.45	6.8 ± 1.9**^##	8.6 ± 2.4**

Note:** compared with the control group, P < 0.01. ^## compared with the active control group, P < 0.01

ISSN: 2662-7671