Table 4 Food consumption during the 13-week administration of HT047
From: Safety evaluation of root extract of Pueraria lobata and Scutellaria baicalensis in rats
Weeks | Male dose (mg/kg/day) | Female dose (mg/kg/day) | ||||||
|---|---|---|---|---|---|---|---|---|
0a | 800 | 2000 | 5000 | 0a | 800 | 2000 | 5000 | |
0b | 24.7 ± 2.2c | 24.8 ± 1.5 | 25.5 ± 2.9 | 25.4 ± 1.9 | 22.0 ± 2.1 | 21.3 ± 2.7 | 21.2 ± 2.0 | 20.3 ± 2.3 |
1 | 28.2 ± 2.5 | 27.7 ± 1.8 | 28.1 ± 2.3 | 27.6 ± 2.2 | 22.3 ± 1.6 | 20.1 ± 1.4** | 19.9 ± 1.5** | 18.8 ± 3.0** |
2 | 31.7 ± 3.2 | 30.7 ± 3.0 | 31.8 ± 3.1 | 31.9 ± 2.3 | 24.2 ± 2.2 | 21.8 ± 1.6* | 19.9 ± 1.7** | 19.8 ± 2.8** |
3 | 32.2 ± 3.8 | 31.2 ± 3.8 | 32.4 ± 2.7 | 33.4 ± 3.3 | 25.3 ± 2.7 | 22.4 ± 3.0* | 20.7 ± 2.3** | 20.4 ± 2.9** |
4 | 32.5 ± 3.7 | 30.9 ± 3.3 | 32.5 ± 2.7 | 34.5 ± 3.0 | 26.2 ± 2.7 | 21.5 ± 1.9** | 20.5 ± 1.9** | 20.8 ± 3.5** |
5 | 33.4 ± 3.8 | 31.3 ± 2.7 | 34.2 ± 3.3 | 35.5 ± 3.2 | 26.8 ± 3.1 | 22.9 ± 1.9## | 21.9 ± 1.2## | 22.3 ± 3.8## |
6 | 33.5 ± 4.1 | 31.4 ± 2.6 | 35.3 ± 3.2 | 35.3 ± 3.5 | 26.5 ± 3.1 | 22.4 ± 2.2## | 23.1 ± 1.6## | 22.4 ± 4.0# |
7 | 33.7 ± 4.4 | 31.3 ± 2.5 | 35.7 ± 2.7 | 35.8 ± 4.0 | 25.6 ± 3.4 | 22.1 ± 1.3## | 23.0 ± 2.3 | 22.2 ± 3.2# |
8 | 33.5 ± 4.4 | 30.7 ± 2.8 | 34.7 ± 2.9 | 34.9 ± 3.8 | 24.9 ± 2.8 | 20.9 ± 2.0** | 22.2 ± 2.0* | 21.7 ± 3.2** |
9 | 33.7 ± 4.4 | 29.8 ± 2.5* | 33.3 ± 3.6 | 35.0 ± 3.8 | 24.2 ± 3.1 | 21.8 ± 2.2 | 22.3 ± 1.8 | 21.1 ± 3.2* |
10 | 33.2 ± 4.7 | 29.8 ± 2.9 | 32.9 ± 3.0 | 34.2 ± 4.1 | 23.9 ± 2.5 | 21.6 ± 1.5 | 22.4 ± 3.0 | 21.6 ± 3.0 |
11 | 33.2 ± 5.0 | 30.1 ± 2.5 | 32.4 ± 3.5 | 33.8 ± 3.7 | 23.3 ± 2.4 | 20.1 ± 1.4## | 21.7 ± 2.5 | 21.3 ± 3.7 |
12 | 32.7 ± 5.2 | 30.1 ± 2.5 | 31.4 ± 3.7 | 32.6 ± 4.0 | 22.3 ± 2.4 | 19.6 ± 2.0 | 21.3 ± 3.1 | 20.8 ± 3.1 |
13 | 31.2 ± 4.3 | 28.8 ± 1.9 | 31.5 ± 3.1 | 32.0 ± 4.4 | 21.1 ± 2.1 | 19.7 ± 2.3 | 20.7 ± 2.8 | 20.3 ± 4.1 |