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Table 3 Body weight changes during the recovery period in the subchronic toxicity study of HT047

From: Safety evaluation of root extract of Pueraria lobata and Scutellaria baicalensis in rats

Weeks

Male dose (mg/kg/day)

Female dose (mg/kg/day)

0a

5000

0a

5000

13b

540.4 ± 59.8c

530.8 ± 63.6

323.3 ± 28.4

263.8 ± 33.0#

14

547.8 ± 61.0

533.4 ± 66.5

330.7 ± 31.3

281.8 ± 34.6#

15

558.4 ± 61.5

547.4 ± 70.3

334.9 ± 35.2

293.1 ± 36.5

16

569.3 ± 61.6

564.0 ± 72.0

339.8 ± 34.4

300.1 ± 40.0

17

576.8 ± 64.4

567.1 ± 72.9

341.8 ± 33.1

304.9 ± 41.3

  1. a Distilled water (10 mL/kg/day)
  2. b The first day of the recovery period was designated week 13
  3. c Data are expressed as mean ± SD in grams (n = 5 per group)
  4. # p < 0.05 vs. control by Student’s t-test