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Table 1 Body weight changes after a single dose of HT047

From: Safety evaluation of root extract of Pueraria lobata and Scutellaria baicalensis in rats

Sexes

Dose (mg/kg)

Days after dosing

Gain

0a

1

3

7

14

0–14

Male

0b

153.1 ± 2.4

177.1 ± 4.2

197.4 ± 5.2

238.6 ± 7.1

307.8 ± 16.4

154.7 ± 14.7

5000

154.8 ± 1.2

177.8 ± 1.8

198.7 ± 1.6

239.4 ± 2.4

310.0 ± 2.5

155.2 ± 2.2

Female

0b

132.9 ± 4.3

154.4 ± 5.6

165.3 ± 7.4

183.4 ± 9.1

213.6 ± 10.4

80.7 ± 10.8

5000

133.5 ± 4.1

155.8 ± 3.4

166.6 ± 4.5

181.6 ± 6.0

208.5 ± 13.6

75.0 ± 9.8

  1. a The day of administration
  2. b Distilled water (10 mL/kg)
  3. Data are expressed as mean ± SD in grams (n = 5 per group)