Fig. 2

Morphologic changes in MDA-MB-231 cells exposed to F. crocata extracts. The images are representative of cells treated for 48 h with FBS 5% (a), V: Vehicle, DMSO (b), 100 μM Ara-C (cytosine β-D-arabinofuranoside) (c), and 20 μg mL^− 1 of Hex-EFc (d), Dic-EFc (e), and Ace-EFc (f). The treatment induced a decrease in cell size (blue arrow), rounded shape (white arrow), and the formation of intracellular vacuoles (black arrow). 20× magnification