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Table 1 Results of enriched GO biological process and KEGG signal pathway analysis results of for module A ~ D (only top three are reserved)

From: Analysis of the pharmacological mechanism of Banxia Xiexin decoction in treating depression and ulcerative colitis based on a biological network module

Module GO Function P-Value KEGG Signaling Pathway P-Value
A GO:0045944 ~ positive regulation of transcription from RNA polymerase II promoter 1.84E-10 hsa05200:Pathways in cancer 3.42E-10
GO:0045429 ~ positive regulation of nitric oxide biosynthetic process 2.50E-10 hsa05205:Proteoglycans in cancer 4.86E-10
GO:0008284 ~ positive regulation of cell proliferation 1.07E-09 hsa00590:Arachidonic acid metabolism 6.48E-03
B GO:0006367 ~ transcription initiation from RNA polymerase II promoter 1.92E-11 hsa04066:HIF-1 signaling pathway 7.71E-08
GO:0045429 ~ positive regulation of nitric oxide biosynthetic process 1.11E-10 hsa00590:Arachidonic acid metabolism 1.86E-03
GO:0048146 ~ positive regulation of fibroblast proliferation 3.81E-08 hsa04064:NF-kappa B signaling pathway 4.83E-02
C GO:0005887 ~ integral component of plasma membrane 1.25E-07 hsa04080:Neuroactive ligand-receptor interaction 2.01E-06
GO:0005886 ~ plasma membrane 6.80E-06 hsa04726:Serotonergic synapse 5.14E-03
GO:0007268 ~ chemical synaptic transmission 1.53E-04 hsa04020:Calcium signaling pathway 1.30E-02
D GO:0006805 ~ xenobiotic metabolic process 2.07E-07 hsa00982:Drug metabolism - cytochrome P450 1.06E-04
GO:0008202 ~ steroid metabolic process 3.39E-06 hsa00980:Metabolism of xenobiotics by cytochrome P450 1.36E-04
GO:0042908 ~ xenobiotic transport 9.81E-06 hsa00830:Retinol metabolism 3.65E-03