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Table 3 Comparison of renal function parameters in rats (mean ± SD, n = 6)

From: Effect of Alpina oxyphylla extract on streptozotocin-induced kidney injure via regulating TGF-β1 and MyD88

 

Nomal

STZ

STZ-gli

AOE 800

AOE 400

Scr (umol/L)

90.12 ± 4.90

125.32 ± 7.05**

112.4 ± 12.36

107.83 ± 11.66##

140.82 ± 8.32#

BUN (mmol/L)

4.60 ± 0.99

13.64 ± 3.54**

9.77 ± 2.42#

9.53 ± 2.38##

13.04 ± 2.52

TG (mmol/L)

0.11 ± 0.04

0.14 ± 0.10*

0.19 ± 0.07

0.07 ± 0.01##

0.11 ± 0.05

TC (mmol/L)

1.62 ± 0.29

3.88 ± 0.68

2.24 ± 0.21#

1.52 ± 0.21##

2.08 ± 0.42##

HDL-C (mmol/L)

0.58 ± 0.11

1.27 ± 0.17**

0.79 ± 0.14##

0.85 ± 0.09##

1.06 ± 0.12#

GSH (umol/L)

21.20 ± 0.37

22.80 ± 1.20

19.07 ± 1.44##

19.10 ± 1.57##

21.86 ± 1.74

IL-6 (pg/mL)

0.43 ± 0.05#

0.49 ± 0.10*

0.44 ± 0.04#

0.41 ± 0.03##

0.40 ± 0.03##

  1. Compared with the normal group, *P < 0.05, ** < 0.01
  2. Compared with the STZ group, #P < 0.05, ## < 0.01