Effectiveness and cerebral responses of multi-points acupuncture for primary insomnia: a preliminary randomized clinical trial and fMRI study

Table 9 The altered fALFF in brain regions of N-Acu group after 5-weeks acupuncture

Brain regions	BA	Side	Cluster size	MNI			t-value
Brain regions	BA	Side	Cluster size	X	Y	Z	t-value
Superior Frontal Gyrus		L	34	−21	63	3	4.63
Superior Frontal Gyrus	10	R	364	21	60	6	5.38
Medial Frontal Gyrus
Anterior Cingulate
Insula	13	L	30	−33	21	6	4.16
Middle Frontal Gyrus	46	L	33	−45	36	21	4.49
Middle Frontal Gyrus	46	R	83	42	24	24	4.44
Inferior Frontal Gyrus	9	R	51	57	6	36	5.09

The anatomical locations, approximate Brodmann areas (BA) and MNI coordinates that corresponded to the t-values of the representative peaks within each cluster were reported. A positive t-value means that fALFF was increased in this brain region after acupuncture treatment. All regions reached a voxel-level significance threshold of P < 0.001, FWE correct P = 0.05, cluster size> 30

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