Effectiveness and cerebral responses of multi-points acupuncture for primary insomnia: a preliminary randomized clinical trial and fMRI study

Table 7 The altered fALFF in brain regions of S-Acu group after 5-weeks acupuncture

Brain regions	BA	Side	Cluster size	MNI			t-value
Brain regions	BA	Side	Cluster size	X	Y	Z	t-value
Cerebellum Posterior Lobe		L	94	−15	−78	−51	5.75
Cerebellum Posterior Lobe		R	40	6	−63	−54	5.30
Cerebellum Posterior Lobe		R	30	42	−66	− 54	5.09
Cerebellum Posterior Lobe		R	49	6	−54	−39	5.25
Brainstem		R	117	18	−18	− 39	6.46
Brainstem		L	30	−6	− 15	−18	5.55
Inferior Temporal Gyrus	20	R	33	60	−24	−21	5.22
Middle Temporal Gyrus		L	40	−66	−45	−18	7.72
Superior Temporal Gyrus	39	L	47	−57	−57	21	6.02
Parahippocampa Gyrus	30	R	42	15	−33	−6	5.52
Precuneus	31	L	42	− 3	−51	30	4.56
Superior Frontal Gyrus	6	L	38	−12	9	72	6.59
Superior Frontal Gyrus	6	R	30	9	0	72	6.00

The anatomical locations, approximate Brodmann areas (BA) and MNI coordinates that corresponded to the t-values of the representative peaks within each cluster were reported. A positive t-value means that fALFF was increased in this brain region after acupuncture treatment. All regions reached a voxel-level significance threshold of P < 0.001, FWE correct P = 0.05, cluster size> 30