Effectiveness and cerebral responses of multi-points acupuncture for primary insomnia: a preliminary randomized clinical trial and fMRI study

Table 6 The relationship between the fALFF value of brain regions and AIS scores of PI

Brain regions	BA	Side	Cluster size	MNI			t-value
Brain regions	BA	Side	Cluster size	X	Y	Z	t-value
Cerebellum Posterior Lobe		R	37	9	−42	−60	−5.42
Middle Temporal Gyrus		L	34	−57	− 57	−3	−6.25
Middle Temporal Gyrus	22	L	217	−57	−42	0	−7.53
Superior Temporal Gyrus	22	L	217	−57	−42	0	−7.53
Parahippocampa Gyrus		L	36	−24	−27	−27	−5.56
Extra-Nuclear		L	79	−21	27	0	−5.67
Anterior Cingulate		R	345	9	30	18	−5.81
Inferior Frontal Gyrus		R	345	9	30	18	−5.81
Middle Frontal Gyrus	9 6	L	1599	−24	27	27	−7.08
Inferior Frontal Gyrus
Superior Frontal Gyrus
Precentral Gyrus	9	R	325	24	6	27	−6.76
Inferior Frontal Gyrus	9	R	325	24	6	27	−6.76
Precentral Gyrus	6	R	54	66	−3	27	−5.03
Supramarginal Gyrus	40	L	345	−54	−48	36	−7.07
Inferior Parietal Lobule
Postcentral Gyrus
Superior Parietal Lobule	19	L	527	−30	−72	48	−6.15
Precuneus	19	L	527	−30	−72	48	−6.15
Superior Frontal Gyrus	8	R	59	24	12	51	−5.49
Superior Frontal Gyrus	6	L	55	−3	18	66	−5.89

The anatomical locations, approximate Brodmann areas (BA) and MNI coordinates that corresponded to the t-values of the representative peaks within each cluster were reported. A negative t-value means that fALFF was lower in this brain region when the AIS value is higher. All regions reached a voxel-level significance threshold of P < 0.001, FWE correct P = 0.05, cluster size> 30

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