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Table 10 The different altered fALFF regions of different groups after acupuncture treatment

From: Effectiveness and cerebral responses of multi-points acupuncture for primary insomnia: a preliminary randomized clinical trial and fMRI study

Group Brain regions BA Side Cluster size MNI t-value
X Y Z
S vs N Anterior Cingulate 25 R 51 3 18 −9 −5.12
Insula   L 168 −15 30 15 −6.93
Cerebellum Posterior Lobe   L 84 −15 −57 −57 4.51
Brainstem   R 38 6 −24 −39 4.56
S vs M Parahippocampa Gyrus   L 35 −27 − 36 −15 −5.18
Superior Temporal Gyrus Middle Temporal Gyrus 22 L 348 −57 −18 −3 − 5.83
Superior Temporal Gyrus   R 31 45 −39 9 −5.02
Lentiform Nucleus   R 91 18 9 0 −4.92
Middle Frontal Gyrus   L 37 −30 42 18 −5.09
Middle Frontal Gyrus   L 33 −36 15 42 −4.69
Middle Frontal Gyrus 6 L 50 −27 0 66 −4.66
Precentral Gyrus   L 126 −51 0 12 −5.40
Inferior Frontal Gyrus
Inferior Frontal Gyrus 9 L 46 −48 3 27 −5.58
Postcentral Gyrus 40 L 152 −48 −27 39 −4.61
Inferior Parietal Lobule
Superior Parietal Lobule 7 L 55 −33 −69 48 −5.09
Anterior Cingulate   L 62 −24 27 24 −5.32
Supramarginal Gyrus 40 L 110 −54 −48 36 −5.73
Angular Gyrus
Precuneus 39 R 33 36 −69 42 −4.59
  1. The anatomical locations, approximate Brodmann areas (BA) and MNI coordinates that corresponded to the t-values of the representative peaks within each cluster were reported. S vs N S-Acu group vs N-Acu group. A positive t-value means that the increased fALFF in this brain region of S-Acu group was higher than that of N-Acu group. S vs M S-Acu group vs M-Acu group. A negative t-value means that the increased fALFF in this brain region of S-Acu group was lower than that of M-Acu group. All regions reached a voxel-level significance threshold of P < 0.005, FWE correct P = 0.05, cluster size> 30
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