Table 4 Databases created and/or updated within the last 3 years identified via eligible articles

American Botanical Council

http://abc.herbalgram.org/site/PageServer

The American Botanical Council provides a searchable database titled “ABC Clinical Guide to Herbs” that includes monographs, clinical overviews, and patient information sheets for various herbs. While access to this database requires a paid subscription, the resource also offers free databases with information on herbal and plant-based ingredients, herb profiles and select herbal monographs.

Caremark Drug Interactions

http://cpref.goldstandard.com/inter.asp?r=8084

Copyrighted through Gold Standard, the Caremark Drug Interactions database includes a drug-interaction search tool. Reports are provided for interactions between drugs, CAM, food, alcohol, and other substances.

Danish National Drug Interaction Database

http://www.interaktionsdatabasen.dk/

The Danish Medicines Agency provides a searchable interactive database for prescription drugs, herbal remedies, vitamins, minerals, and grapefruit juice.

Drug Information- formerly named DrugDigest

https://www.express-scripts.com/medco/consumer/ehealth/druginfo/dlmain.jsp?WC=N

The Drug Information database includes a search tool to find monographs and information on medications, herbal drugs, and supplements. While several drugs are indexed in the database, the majority of drugs do not have a monograph available.

Drug Product Database

https://www.canada.ca/en/health-canada/services/drugs-health-products/drug-products/drug-product-database.html

The Drug Product Database is maintained by Health Canada through the Government of Canada and contains a searchable database for drugs authorized for sale in Canada. While several drugs are indexed in the database, many do not have product monographs available.

DrugBank

https://www.drugbank.ca/

The Drugbank database provides information on drugs and drug/chemical target information.

Encyclopedia of Traditional Chinese Medicine (ETCM)

http://www.nrc.ac.cn:9090/ETCM/

ETCM is an online searchable database that provides data on the ingredients, herbs, and formulas of Traditional Chinese Medicine.

PharmGKB

https://www.pharmgkb.org

PharmGKB is a searchable pharmacogenomic database targeted for researchers that provides data on the relationship between genetic variations and drug response. Molecules, genes, or variants can be searched within the database.

Traditional Chinese Medicine Information Database (TCM-ID)

http://119.3.41.228:8000/tcmid/

In its second revision, the TCM-ID database provides information on the relationships between the herbs and formulas and the pharmacology or biochemistry of Traditional Chinese Medicine.

Clinical Pharmacology

https://www.clinicalpharmacology.com/

Clinical Pharmacology is a drug information resource that is powered by Clinical Key and owned by Gold Standard. The database contains monographs for prescription drugs as well as CAM products.

DrDrugs

https://www.skyscape.com/product/drdrugs-drug-guide-for-physicians

DrDrugs provides a mobile and web-based database of monographs for drugs and herbal products.

Epocrates Rx (plus or pro)

https://online.epocrates.com/

Epocrates offers a web-based and mobile version of their database of drug monographs and interaction reports.

Lexi-Natural (includes LexiComp)

http://webstore.lexi.com/Store/Individual-Databases/Lexi-Natural-Products

Lexi-Natural is part of the Lexicomp database and includes drug monographs and patient handouts for both prescription drugs and CAM products.

MedicinesComplete (includes Herbal Medicines; formerly known as the British National Formulary)

https://about.medicinescomplete.com/publication/herbal-medicines/

Developed by the Royal Pharmaceutical Society, MedicinesComplete provides a database of drug and CAM monographs and drug interaction reports.

Micromedex (includes DrugDex, Drug-Reax, AltMedDex)

https://www.micromedexsolutions.com/home/dispatch/ssl/true

IBM Micromedex provides a searchable database of drug and CAM monographs as well as disease and toxicology

Natural Medicines (formerly Natural Medicine Comprehensive Database (NMCD) and Natural Standard Database (NSD))

https://naturalmedicines.therapeuticresearch.com/

Natural Medicines is a database with several sub-databases on databases on food, herbs and supplements, herbal combinations, drug manufacturers, sports medicine, health and wellness and a comparative effectiveness database. The database also features tools including an interaction checker, effectiveness checker, nutrient depletion, pregnancy and lactation checker and adverse event checker.

OncoRx Database (called Onco-Rx as a website, and OncoRx-MI as a mobile app)

http://www.onco-informatics.com/oncorx/

Onco Rx is a database of interaction information for oncology drugs, chemotherapy regimens and CAM products.

PEPID Drug Information Database

https://www.pepid.com/

PEPID Knowledgebase is a web-accessible database hosted through PEPID Connect. Features of PEPID Connect include: Drug interaction checker; drug-allergy checker; pill identification; IV Compatibility tool; lab manuals; clinical calculators; drug database; differential diagnosis and symptom checker; news and alerts; PEPID PGx pharmacogenomic tool.

Tarascon Pocket Pharmacopoeia

https://www.tarascon.com/products/mobile/

The Tarascon Pocket Pharmacopoeia database contains drug guides and information on drug interactions. The database comes in a PDA format and also includes information on herbal supplements.