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Table 1 UHPLC-MS/MS quantification analysis of major compounds of Phyllanthus amarus

From: Phyllanthus amarus prevents LPS-mediated BV2 microglial activation via MyD88 and NF-κB signaling pathways

Compound

Concentration

(mg mL− 1)

LODa

(mg mL− 1)

LOQb

(mg mL− 1)

R2

RSD (%)

Phyllanthin

0.034 ± 0.002

1.0 × 10− 6

3.0 × 10− 6

0.999

6.071

Hypophyllanthin

0.026 ± 0.001

1.1 × 10− 6

3.7 × 10− 6

0.999

4.417

Niranthin

0.056 ± 0.001

2.0 × 10− 6

7.0 × 10− 6

0.997

3.412

Ellagic acid

0.116 ± 0.001

1.5 × 10− 6

5.0 × 10− 5

0.999

4.061

Corilagin

0.061 ± 0.001

2.7 × 10− 6

5.7 × 10− 6

0.999

4.08

Gallic acid

0.024 ± 0.001

1.2 × 10− 6

4.0 × 10− 5

1

3.512

Phyltetralin

< 0.0001 ± 0.129

1.0 × 10− 6

3.0 × 10− 5

0.999

4.311

Isolintetralin

0.017 ± 0.002

1.0 × 10− 6

3.0 × 10− 5

0.995

4.312

Geraniin

0.031 ± 0.029

1.0 × 10− 6

3.0 × 10− 6

0.9990

2.34

  1. aLimit of detection, bLimit of quantification