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Table 2 General characteristics of included studies

From: African potato (Hypoxis hemerocallidea): a systematic review of its chemistry, pharmacology and ethno medicinal properties

Study number

Study design

Author, year [reference]

Data extracted

1.

Clinical trial

Albrecht et al., 1995 [15]

Safety of β-sitosterol; dose and metabolic pathway of hypoxoside

2.

Donald et al., 1997 [16]

Pharmacological effects of phytosterols

3.

Mogatle et al., 2008 [17]

African potato drug interactions

4.

Gwaza et al., 2013 [18]

African potato drug interactions

5.

Berges et al., 1995 [19]

Clinical properties, the dosage of β-sitosterol

6.

Pilot study, open-label intervention

Bouic et al., 2001 [20]

Pharmacological effects of β-sitosterol

7.

Quantitative, experimental

Boukes GJ et al., 2010 [21]

Pharmacology

8.

Awad et al., 2000 [22]

Mechanism of action

9.

Bouic et al., 1996 [23]

Pharmacology and bioavailability of β-sitosterol

10.

Lamprecht et al., 2000 [24]

β-sitosterol and the glucoside mixture improving CD4 count

11.

Albrecht et al., 1995 [25]

Mechanism of action, metabolism and pharmacokinetics of hypoxoside

12.

Kruger et al., 1994 [26]

Metabolism of hypoxoside

13.

Nair et al. 2007, [27]

Metabolism of African potato

14.

Gwaza et al., 2009 [28]

Drug interactions of hypoxis extracts

15–22.

Experimental preclinical (in vivo)

As shown in Table 3

Pharmacologic activities of Africa Potato in different species

23.

Qualitative screening

Zimudzi C, 2014 [1]

Chemistry

24.

Nair et al., 2006 [37]

Dosage of African potato

25.

Systematic review

Ncube et al., 2013 [38]

Uses of African potato and dosage forms (and strengths) available

26.

Narrative review

Drewes SE et al., 2008 [10]

Chemistry, ethnopharmacological properties

27.

Mills E et al., 2005 [11]

Pharmacology, chemistry, ethnopharmacological properties

28.

Bouic 2001, [39]

Chemistry and pharmacological uses

29.

Ling et al.,1995 [40]

Pharmacological uses, mechanism of action of phytosterols

30.

Saeidnia et al., 2014 [41]

Pharmacological effects

31.

Not applicable - Website

Natures Health website, [42]

Dosage of African potato capsules

32.

Green Herbs & Nutrition’s Stores website, [43]

Dosage of African potato capsules

33.

Puer Orijins catalogue, [44]

Other dosage forms available