Targets | Official name | Degree | BC | CC |
---|---|---|---|---|
TP53 | Tumor protein p53 | 102 | 0.082 | 0.557 |
MAPK1 | Mitogen-activated protein kinase 1 | 95 | 0.037 | 0.539 |
AKT1 | AKT serine/threonine kinase 1 | 93 | 0.029 | 0.533 |
VEGFA | Vascular endothelial growth factor A | 90 | 0.033 | 0.538 |
INS | Insulin | 86 | 0.087 | 0.547 |
IL6 | Interleukin 6 | 86 | 0.047 | 0.54 |
STAT3 | Signal transducer and activator of transcription 3 | 85 | 0.017 | 0.519 |
PIK3CA | Phosphatidylinositol-4,5-Bisphosphate 3-Kinase Catalytic Subunit Alpha | 84 | 0.037 | 0.519 |
MAPK8 | Mitogen-activated protein kinase 8 | 83 | 0.029 | 0.529 |
MAPK3 | Mitogen-activated protein kinase 3 | 83 | 0.027 | 0.532 |
SRC | SRC Proto-Oncogene, Non-Receptor Tyrosine Kinase | 81 | 0.027 | 0.513 |
APP | Amyloid beta precursor protein | 77 | 0.072 | 0.514 |
JUN | Jun proto-oncogene, AP-1 transcription factor subunit | 77 | 0.028 | 0.532 |
EGFR | Epidermal growth factor receptor | 74 | 0.027 | 0.518 |
HRAS | HRas Proto-Oncogene, GTPase | 70 | 0.014 | 0.503 |
IGF1 | Insulin like growth factor 1 | 70 | 0.013 | 0.511 |
CTNNB1 | Catenin beta 1 | 66 | 0.033 | 0.498 |
TNF | Tumor necrosis factor | 66 | 0.011 | 0.505 |
MYC | MYC proto-oncogene, bHLH transcription factor | 62 | 0.012 | 0.498 |
MMP9 | Matrix metallopeptidase 9 | 59 | 0.024 | 0.498 |
FGF2 | Fibroblast growth factor 2 | 58 | 0.01 | 0.495 |
FOS | Fos proto-oncogene, AP-1 transcription factor subunit | 54 | 0.015 | 0.498 |
CASP3 | Caspase 3 | 54 | 0.011 | 0.492 |
CCND1 | Cyclin D1 | 54 | 0.004 | 0.475 |
PTEN | Phosphatase and tensin homolog | 53 | 0.005 | 0.474 |
RELA | RELA proto-oncogene, NF-kB subunit | 52 | 0.007 | 0.487 |
HGF | Hepatocyte growth factor | 51 | 0.006 | 0.484 |
BDNF | Brain derived neurotrophic factor | 50 | 0.021 | 0.498 |
CDH1 | Cadherin 1 | 50 | 0.013 | 0.487 |