Skip to main content

Table 2 Effect of treatment with A. machrostachyum at two doses on cell cycle regulatory and apoptosis-related genes as assessed by qPCR

From: Therapeutic effect of Arthrocnemum machrostachyum methanolic extract on Ehrlich solid tumor in mice

Group

P53

Bax

Caspase3

Bcl2

Cdc2

Connexin26

Negative control

1 c

1 c

1 c

1 a

1 b

1 c

EST

1.04 ± 0.10 c

0.87 ± 0.11 c

0.98 ± 0.08 c

1.08 ± 0.09 a

0.87 ± 0.06 b

0.93 ± 0.07 c

A. machrostachyum (180 mg/ kg)

3.21 ± 0.19 b

2.43 ± 0.13 b

1.92 ± 0.12 b

0.26 ± 0.03 b

1.83 ± 0.10 a

1.94 ± 0.11 b

A. machrostachyum (360 mg/ kg)

7.92 ± 0.35 a

3.85 ± 0.15 a

2.8 ± 0.15 a

0.10 ± 0.01 c

2.08 ± 0.09 a

2.87 ± 0.14 a

  1. Data are expressed as fold change mean ± SEM (n = 7). Values with different superscript letters [a (the highest value) – c (the lowest value)] in the same column are significantly different at p < 0.05. All groups were compared to each other for each gene