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Table 3 Correlations between components and targets

From: Uncovering the mechanism of the effects of Paeoniae Radix Alba on iron-deficiency anaemia through a network pharmacology-based strategy

Components

Downregulate

Upregulate

References

Paeoniflorin

TNF,IL6,PTGS2,CYP3A4,CASP3

PPARG,CAT

[52,53,54,55,56,57,58]

Albiflorin

TNF,IL6,PTGS2,CYP3A4,CASP3

NOS3

[52, 54, 57, 59]

β-Sitosterol

IL6,PTGS2,TNF,CYP3A4,CASP3

PPARG,CAT,NOS3

[60,61,62,63,64]

Mairin

PTGS2,TNF,CYP3A4,IL6,CASP3,

PPARG,CAT

[65,66,67,68,69]

(+)-Catechin

TNF,PTGS2,CYP3A4,IL6,CASP3,JUN

PPARG,ESR1,TP53

[70,71,72,73,74,75,76]

Kaempferol

PTGS2,CYP3A4,TNF,IL6,CASP3,JUN

PPARG,CAT

[77,78,79,80,81,82]

Gallic acid

PTGS2,CYP3A4,IL6,TNF,CASP3

PPARG,CAT,NOS3

[61, 83,84,85,86,87]

Benzoylpaeoniflorin

PTGS2,IL6,TNF

 

[53, 84]