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Table 3 Correlations between components and targets

From: Uncovering the mechanism of the effects of Paeoniae Radix Alba on iron-deficiency anaemia through a network pharmacology-based strategy

ComponentsDownregulateUpregulateReferences
PaeoniflorinTNF,IL6,PTGS2,CYP3A4,CASP3PPARG,CAT[52,53,54,55,56,57,58]
AlbiflorinTNF,IL6,PTGS2,CYP3A4,CASP3NOS3[52, 54, 57, 59]
β-SitosterolIL6,PTGS2,TNF,CYP3A4,CASP3PPARG,CAT,NOS3[60,61,62,63,64]
MairinPTGS2,TNF,CYP3A4,IL6,CASP3,PPARG,CAT[65,66,67,68,69]
(+)-CatechinTNF,PTGS2,CYP3A4,IL6,CASP3,JUNPPARG,ESR1,TP53[70,71,72,73,74,75,76]
KaempferolPTGS2,CYP3A4,TNF,IL6,CASP3,JUNPPARG,CAT[77,78,79,80,81,82]
Gallic acidPTGS2,CYP3A4,IL6,TNF,CASP3PPARG,CAT,NOS3[61, 83,84,85,86,87]
BenzoylpaeoniflorinPTGS2,IL6,TNF [53, 84]