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Table 4 Enzyme inhibitory activity of the extracts of Evolvulus alsionoides (Linn.) Linn

From: In vitro enzyme inhibitory and cytotoxic studies with Evolvulus alsinoides (Linn.) Linn. Leaf extract: a plant from Ayurveda recognized as Dasapushpam for the management of Alzheimer’s disease and diabetes mellitus

S.No.

Extract

α – Amylase

IC50, μg/ml

α – Glucosidase

IC50, μg/ml

Acetyl cholinesterase

IC50, μg/ml

1.

H

12.35 ± 0.2

8.10 ± 0.1

6.61 ± 0.07

2.

C

14.96 ± 0.05

11.19 ± 0.13

7.55 ± 0.08

3.

EA

7.65 ± 0.1

4.82 ± 0.14

6.03 ± 0.03

4.

M

1.33 ± 0.05

3.80 ± 0.09

4.77 ± 0.04

5.

W

1.34 ± 0.08

3.58 ± 0.02

4.46 ± 0.03

6.

Standarda

1.32 ± 0.15

6.46 ± 0.1

2.59 ± 0.09

  1. aAcarbose was used as the standard drug in α-amylase and α-glucosidase assays, galantamine in acetylcholinesterase