Fig. 12

Protective effects of SMI on DOX-induced cardiotoxicity in mice. a Body weight. n = 10–25. b Heart weight to body weight ratios (HW/BW). n = 5–15. c-e The levels of CK, CK-MB and LDH in mouse serum. n = 7–22. f Representative M-mode echocardiograms of mice. g-i Echocardiographic measurement of left ventricular ejection fraction (EF%), fractional shortening (FS%), and left ventricular posterior wall (LVPW; s). n = 10–26. *P < 0.05 vs. Control group; **P < 0.01 vs. Control group; ^#P < 0.05 vs. DOX group