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Table 6 Some biochemical parametres of rats after 6 months of treatment with the aqueous extract of C. molle

From: Chronic oral safety study of the aqueous extract of Combretum molle twigs on biochemical, haematological and antioxidant parameters of Wistar rats

ParametersGroups
Control62.5 mg/kg125 mg/kg250 mg/kg
Glucose (mg/dL)82.2 ± 2.586.9 ± 2.379.7 ± 1.876.4 ± 2.4
T. protein (g/dL)8.31 ± 0.657.42 ± 0.488.79 ± 0.289.18 ± 0.48
T. biliribin (μmol/L)12.46 ± 0.9313.30 ± 1.0913.79 ± 1.2114.24 ± 1.37
Albumin (g/L)46.55 ± 2.9341.53 ± 3.2341.70 ± 3.9339.14 ± 3.21
ALT (U/L)98.60 ± 6.095.11 ± 10.16103.75 ± 4,1957.47 ± 8.33**
AST (U/L)110.22 ± 4.9097.18 ± 7.2985.73 ± 5.01*82.73 ± 7.19*
ALP (U/L)93.37 ± 4.6295.37 ± 4.8583.38 ± 6.2599.93 ± 4.08
Cholesterol (mg/dL)99.24 ± 4.87107.27 ± 3.02109.40 ± 5.6989.55 ± 1.83
Triglycerides (mg/dL)75.82 ± 3.6090.84 ± 5.4284.92 ± 5.1444.59 ± 4.35***
HDLc (mg/dL)52.77 ± 6.6878.94 ± 3.83**81.35 ± 5.80**75.12 ± 3.71**
LDLc (mg/dL)31.31 ± 2.6810.16 ± 0.58***11.03 ± 1.23***5.51 ± 1.96***
VLDL (mg/dL)15.16 ± 0.7218.17 ± 1.0817.02 ± 1.028.92 ± 0.87***
Serum creat (mg/dL)0.72 ± 0.040.63 ± 0.040.59 ± 0.020.55 ± 0.03**
Urine creat (mg/dL)0.58 ± 0.030.62 ± 0.030.66 ± 0.030.70 ± 0.04
Creat.CR (mL/min)3.56 ± 0.244.37 ± 0.364.93 ± 0.35*4.95 ± 0.39*
Urea (mg/dL)47.51 ± 2.6157.13 ± 3.4751.34 ± 3.6441.47 ± 3.13
Uric acid (mg/dL)13.08 ± 0.7911.01 ± 0.8613.53 ± 1.1512.07 ± 1.03
  1. Values are expressed as mean ± SD, n = 10. (One-way ANOVA followed by Turkey’s post-hoc test). *P < 0.05; **P < 0.01; ***P < 0.001 significantly different when compared to the control group