A mechanistic approach to HPLC analysis, antinociceptive, anti-inflammatory and postoperative analgesic activities of panch phoron in mice

Table 3 Effect of PPE on tail-flick test in mice

Treatment	Dose	0 s	30 min	60 min
Control (distilled water)	10 ml/kg	3.2 ± 0.1	2.7 ± 0.6	2.4 ± 0.4
Na diclofenac	10 mg/kg	3.1 ± 0.1*	4.0 ± 0.1*	4.2 ± 0.1*
PPE	100 mg/kg	2.5 ± 0.3*	4.1 ± 0.7*	4.4 ± 0.7*
PPE	250 mg/kg	3.2 ± 0.4*	4.8 ± 0.2*	6.2 ± 0.6*
PPE	500 mg/kg	3.6 ± 0.2*	5.6 ± 0.2*	7.8 ± 0.8*

N = 6. Values are mean ± SEM. *p < 0.05 compared to control (Repeated measures ANOVA followed by Dunnett’s post hoc test)

ISSN: 2662-7671