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Table 2 Effect of PPE on acetic acid-induced writhing test in mice

From: A mechanistic approach to HPLC analysis, antinociceptive, anti-inflammatory and postoperative analgesic activities of panch phoron in mice

TreatmentDoseNo of writhing% of writhing% of writhing inhibition
Control (distilled water)10 ml/kg39.2 ± 1.3100.00.0
Na diclofenac10 mg/kg13.4 ± 1.3*34.265.8
PPE100 mg/kg35.8 ± 4.2*91.38.7
PPE250 mg/kg24.0 ± 0.7*61.238.8
PPE500 mg/kg18.2 ± 1.7*46.453.6
PPE (500 mg/kg) +
Naloxone (2 mg/kg)
 13.5 ± 0.4*34.465.6
  1. N = 6. Values are mean ± SEM. *p < 0.05 compared to control (One-Way ANOVA followed by Dunnett’s post hoc test)