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Fig. 3 | BMC Complementary Medicine and Therapies

Fig. 3

From: Role of limonin in anticancer effects of Evodia rutaecarpa on ovarian cancer cells

Fig. 3

Molecular pathways involved in the induction of apoptosis by limonin. (a) Caspase-3 activity (mean ± SEM) in SKOV-3 cells treated with synephrine and limonin for 24 h. (b) Immunoblotting analysis of expression levels of p53 and p65 proteins in SKOV-3 cells treated with synephrine (10 μM), limonin (10 μM), or DMSO (control) for 24 h. (c, d) Quantification of p65 (c) and p53 (d) levels (mean ± SEM) in (b). α-Tubulin was used as a loading control. *P < 0.05

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