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Fig. 5 | BMC Complementary Medicine and Therapies

Fig. 5

From: Activation of the Nrf2/HO-1 pathway by curcumin inhibits oxidative stress in human nasal fibroblasts exposed to urban particulate matter

Fig. 5

a Representative Western blots of ERK, SOD2, and HO-1 in fibroblasts treated with 5 μM of curcumin and 25 μg/mL of UPM for 24 h. b Density ratio of p-ERK to ERK. c Density ratios of HO-1 to GAPDH. d Density ratios of SOD2 to GAPDH. e Representative Western blots of Nrf2 in fibroblasts treated with 5 μM of curcumin and 25 μg/mL of UPM for 4 h. f Density ratio of nuclear Nrf2 to nuclear lamin B1. Each value of the graph represents the mean ± SEM of three independent experiments. *p < 0.05 vs. 0 μg/mL of UPM and 0 μM of curcumin; #p < 0.05 vs. 25 μg/mL of UPM. ERK: extracellular signal-regulated kinase; HO-1: haem oxygenase-1; SOD2: superoxide dismutase 2; UPM: urban particulate matter; Nrf2: nuclear factor (erythroid-derived 2)-like 2

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BMC Complementary Medicine and Therapies

ISSN: 2662-7671

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