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Fig. 3 | BMC Complementary Medicine and Therapies

Fig. 3

From: Activation of the Nrf2/HO-1 pathway by curcumin inhibits oxidative stress in human nasal fibroblasts exposed to urban particulate matter

Fig. 3

Expression of HO-1 and SOD2 and phosphorylation of ERK following the exposure of nasal fibroblasts to UPM. a Western blot analysis of phosphorylated ERK (p-ERK), total ERK, HO-1, and SOD2 in human nasal fibroblasts treated with UPM (25 μg/mL) for the indicated durations. b Density ratio of p-ERK to ERK. c Density ratio of HO-1 to GAPDH. d Density ratio of SOD2 to GAPDH. Data are presented as the mean ± SEM. *p < 0.05 and **p < 0.01 vs. the control group. ERK: extracellular signal-regulated kinase; HO-1: heme oxygenase-1; SOD2: superoxide dismutase 2; UPM: urban particulate matter; GAPDH: glyceraldehyde-3-phosphate dehydrogenase

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