Table 1 Information of 30 bioactive compounds in TWH
From: A network pharmacology study on the Tripteryguim wilfordii Hook for treatment of Crohn’s disease
Molecular ID | Molecular name | OB (%) | Caco-2 | DL | HL |
|---|---|---|---|---|---|
MOL003182 | (+)-Medioresinol di-O-beta-D-glucopyranoside_qt | 60.69 | 0.45 | 0.62 | 3.05 |
MOL004443 | Zhebeiresinol | 58.72 | 0.53 | 0.19 | 3.32 |
MOL003279 | 99694-86-7 | 75.23 | −0.13 | 0.66 | 3.71 |
MOL009386 | 3,3′-bis-(3,4-dihydro-4-hydroxy-6-methoxy)-2H-1-benzopyran | 52.11 | 0.14 | 0.54 | 3.76 |
MOL003199 | 3,3′-bis-(3,4-dihydro-4-hydroxy-6-methoxy)-2H-2-benzopyran | 61.85 | 0.02 | 0.54 | 3.97 |
MOL003189 | WILFORLIDE A | 35.66 | 0.31 | 0.72 | 4.05 |
MOL011169 | Peroxyergosterol | 44.39 | 0.86 | 0.82 | 4.06 |
MOL003187 | triptolide | 51.29 | 0.25 | 0.68 | 4.14 |
MOL003232 | Triptofordin B1 | 39.55 | 0.41 | 0.84 | 4.19 |
MOL003211 | Celaxanthin | 47.37 | 1.73 | 0.58 | 4.33 |
MOL003196 | Tryptophenolide | 48.5 | 1.11 | 0.44 | 4.42 |
MOL003188 | Tripchlorolide | 78.72 | 0.16 | 0.72 | 4.44 |
MOL003192 | Triptonide | 67.66 | 0.15 | 0.7 | 4.48 |
MOL000211 | Mairin | 55.38 | 0.73 | 0.78 | 8.87 |
MOL003224 | Tripdiotolnide | 56.4 | −0.29 | 0.67 | 4.91 |
MOL003198 | 5 alpha-Benzoyl-4 alpha-hydroxy-1 beta,8 alpha-dinicotinoyl-dihydro-agarofuran | 35.26 | −0.35 | 0.72 | 5.23 |
MOL000296 | hederagenin | 36.91 | 1.32 | 0.75 | 5.35 |
MOL000358 | beta-sitosterol | 36.91 | 1.32 | 0.75 | 5.36 |
MOL000449 | Stigmasterol | 43.83 | 1.44 | 0.76 | 5.57 |
MOL003184 | 81,827–74-9 | 45.42 | 0.85 | 0.53 | 5.58 |
MOL007415 | [(2S)-2-[[(2S)-2-(benzoylamino)-3-phenylpropanoyl]amino]-3-phenylpropyl] acetate | 58.02 | 0.32 | 0.52 | 6.03 |
MOL007535 | (5S,8S,9S,10R,13R,14S,17R)-17-[(1R,4R)-4-ethyl-1,5-dimethylhexyl]-10,13-dimethyl-2,4,5,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta [a]phenanthrene-3,6-dione | 33.12 | 0.9 | 0.79 | 6.56 |
MOL003266 | 21-Hydroxy-30-norhopan-22-one | 34.11 | 0.9 | 0.77 | 6.66 |
MOL003235 | Triptofordin D1 | 32 | −0.35 | 0.75 | 7.2 |
MOL003244 | Triptonide | 68.45 | 0.15 | 0.68 | 4.79 |
MOL003209 | Celallocinnine | 83.47 | 0.89 | 0.59 | 10 |
MOL000422 | kaempferol | 41.88 | 0.26 | 0.24 | 14.74 |
MOL005828 | nobiletin | 61.67 | 1 | 0.52 | 16.2 |
MOL003280 | TRIPTONOLIDE | 49.51 | 0.72 | 0.49 | 17.94 |
MOL003217 | Isoxanthohumol | 56.81 | 0.76 | 0.39 | 17.98 |