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Table 2 Effects of 28 days oral administration of E. kebericho decoction on absolute organ weight and relative organ weight

From: Acute and sub-acute toxicity of Echinops kebericho decoction in rats

OrgansMaleFemaleP-value
control150 mg/kg300 mg/kg600 mg/kgControl150 mg/kg300 mg/kg600 mg/kg 
Absolute weight
 Liver (in g)11.49 ± 1.0412.13 ± 1.2111.89 ± 2.419.19 ± 0.969.85 ± 2.189.42 ± 0.897.13 ± 0.569.12 ± 0.72
 Right kidney (in g)1.114 ± 0.171.22 ± 0.171.072 ± 0.171.04 ± 0.120.91 ± 0.120.94 ± 0.100.77 ± 0.080.86 ± 0.07
 Left kidney (in g)1.16 ± 0.161.25 ± 0.221.02 ± 0.130.98 ± 0.080.89 ± 0.080.912 ± 0.140.79 ± 0.090.87 ± 0.06
Spleen (in g)0.53 ± 0.040.66 ± 0.130.61 ± 0.160.65 ± 0.110.59 ± 0.160.63 ± 0.080.67 ± 0.070.63 ± 0.10
 Lung (in g)1.80 ± 0.301.86 ± 0.141.59 ± 0.131.59 ± 0.181.65 ± 0.131.44 ± 0.061.30 ± 0.131.19 ± 0.20
 Heart (in g)1.35 ± 0.0421.42 ± 0.231.33 ± 0.201.19 ± 0.111.04 ± 0.041.02 ± 0.071.02 ± 0.131.02 ± 0.06
Relative organ weight (Organ weight in gram/100 g of animal weight)
 Liver3.21 ± 0.263.12 ± 0.213.13 ± 0.482.62 ± 0.353.61 ± 0.703.60 ± 0.183.00 ± 0.243.63 ± 0.370.0045*/0.2187
 Right kidney0.31 ± 0.040.31 ± 0.030.28 ± 0.030.29 ± 0.020.33 ± 0.040.36 ± 0.030.32 ± 0.030.34 ± 0.030.0497*/0.2743
 Left kidney0.32 ± 0.040.32 ± 0.050.27 ± 0.030.28 ± 0.020.33 ± 0.040.35 ± 0.030.33 ± 0.030.34 ± 0.020.0206*/0.2759
 Spleen0.15 ± 0.020.17 ± 0.030.16 ± 0.030.18 ± 0.040.22 ± 0.050.24 ± 0.040.28 ± 0.030.25 ± 0.030.0013* /0.3968
 Lung0.50 ± 0.060.48 ± 0.040.42 ± 0.020.45 ± 0.040.61 ± 0.050.55 ± 0.050.54 ± 0.040.47 ± 0.080.0015* /0.0277**
 Heart0.38 ± 0.020.36 ± 0.050.35 ± 0.040.34 ± 0.020.38 ± 0.010.39 ± 0.020.43 ± 0.070.40 ± 0.040.0409*/0.9093
  1. * Significant p-value when males and females are treated separately, **Significant p-value when males and females are grouped together