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Table 2 Effects of 28 days oral administration of E. kebericho decoction on absolute organ weight and relative organ weight

From: Acute and sub-acute toxicity of Echinops kebericho decoction in rats

Organs

Male

Female

P-value

control

150 mg/kg

300 mg/kg

600 mg/kg

Control

150 mg/kg

300 mg/kg

600 mg/kg

 

Absolute weight

 Liver (in g)

11.49 ± 1.04

12.13 ± 1.21

11.89 ± 2.41

9.19 ± 0.96

9.85 ± 2.18

9.42 ± 0.89

7.13 ± 0.56

9.12 ± 0.72

–

 Right kidney (in g)

1.114 ± 0.17

1.22 ± 0.17

1.072 ± 0.17

1.04 ± 0.12

0.91 ± 0.12

0.94 ± 0.10

0.77 ± 0.08

0.86 ± 0.07

–

 Left kidney (in g)

1.16 ± 0.16

1.25 ± 0.22

1.02 ± 0.13

0.98 ± 0.08

0.89 ± 0.08

0.912 ± 0.14

0.79 ± 0.09

0.87 ± 0.06

–

Spleen (in g)

0.53 ± 0.04

0.66 ± 0.13

0.61 ± 0.16

0.65 ± 0.11

0.59 ± 0.16

0.63 ± 0.08

0.67 ± 0.07

0.63 ± 0.10

–

 Lung (in g)

1.80 ± 0.30

1.86 ± 0.14

1.59 ± 0.13

1.59 ± 0.18

1.65 ± 0.13

1.44 ± 0.06

1.30 ± 0.13

1.19 ± 0.20

–

 Heart (in g)

1.35 ± 0.042

1.42 ± 0.23

1.33 ± 0.20

1.19 ± 0.11

1.04 ± 0.04

1.02 ± 0.07

1.02 ± 0.13

1.02 ± 0.06

–

Relative organ weight (Organ weight in gram/100 g of animal weight)

 Liver

3.21 ± 0.26

3.12 ± 0.21

3.13 ± 0.48

2.62 ± 0.35

3.61 ± 0.70

3.60 ± 0.18

3.00 ± 0.24

3.63 ± 0.37

0.0045*/0.2187

 Right kidney

0.31 ± 0.04

0.31 ± 0.03

0.28 ± 0.03

0.29 ± 0.02

0.33 ± 0.04

0.36 ± 0.03

0.32 ± 0.03

0.34 ± 0.03

0.0497*/0.2743

 Left kidney

0.32 ± 0.04

0.32 ± 0.05

0.27 ± 0.03

0.28 ± 0.02

0.33 ± 0.04

0.35 ± 0.03

0.33 ± 0.03

0.34 ± 0.02

0.0206*/0.2759

 Spleen

0.15 ± 0.02

0.17 ± 0.03

0.16 ± 0.03

0.18 ± 0.04

0.22 ± 0.05

0.24 ± 0.04

0.28 ± 0.03

0.25 ± 0.03

0.0013* /0.3968

 Lung

0.50 ± 0.06

0.48 ± 0.04

0.42 ± 0.02

0.45 ± 0.04

0.61 ± 0.05

0.55 ± 0.05

0.54 ± 0.04

0.47 ± 0.08

0.0015* /0.0277**

 Heart

0.38 ± 0.02

0.36 ± 0.05

0.35 ± 0.04

0.34 ± 0.02

0.38 ± 0.01

0.39 ± 0.02

0.43 ± 0.07

0.40 ± 0.04

0.0409*/0.9093

  1. * Significant p-value when males and females are treated separately, **Significant p-value when males and females are grouped together