Table 1 Antidiarrheal effect of E. hirta extract against castor oil-induced diarrhea in mice
Group no. | Treatment | Dose (mg/kg) | Mean feces/group (numbers) | Mean wet feces/group (numbers) | % age protection from diarrhea |
|---|---|---|---|---|---|
1 | Saline + castor oil (10 mL/kg) | – | 8.5 ± 1.78 | 6.82 ± 0.47 | 18% |
2 | Loperamide + castor oil | 10 | 2.83 ± 0.60 ** | 0 ± 0.00 ** | 100% |
3 | EH Cr. (p.o) + castor oil | 500 | 4.83 ± 0.40 * | 2.85 ± 1.24* | 41% |
4 | EH Cr. (p.o) + castor oil | 1000 | 3.84 ± 0.54 ** | 1.16 ± 1.16** | 70% |
5 | Quercetin + castor oil (p.o) | 50 | 8.16 ± 053 | 4.16 ± 1.07* | 46% |
6 | Quercetin + castor oil (p.o) | 100 | 7.66 ± 0.61 | 3.33 ± 0.91* | 56% |
7 | Quercetin + castor oil (p.o) | 150 | 7.33 ± 0.80 | 2.50 ± 1.41* | 65% |