Table 2 Cytotoxycity of natural and semi-synthetics compounds from A. zygia
Cell lines | Compounds IC50 (μM) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
1 | 2 | 3 | 4 | 5 | 7 | 8 | 9 | 10 | Doxorubicin | |
MCF-7 | 42.7 ± 0.25 | 87.5 ± 0.25 | 46.4 ± 0.25 | 17.3 ± 0.25 | 33.7 ± 0.25 | 37.0 ± 0.25 | 40.2 ± 0.25 | 10.8 ± 0.25 | 64.9 ± 0.25 | < 7 × 10−5 |
A2058 | 66.7 ± 0.25 | 87.5 ± 0.25 | 46.4 ± 0.25 | 34.6 ± 0.25 | 33.7 ± 0.25 | 37.0 ± 0.25 | 40.2 ± 0.25 | 12.2 ± 0.25 | 64.9 ± 0.25 | < 7 × 10−5 |
HepG2 | 121.2 ± 0.25 | 87.5 ± 0.25 | 23.2 ± 0.25 | 17.3 ± 0.25 | 16.8 ± 0.25 | 37.0 ± 0.25 | 40.2 ± 0.25 | 22.6 ± 0.25 | 64.9 ± 0.25 | < 7 × 10−5 |
A-549 | 121.2 ± 0.25 | 89.5 ± 0.25 | 23.2 ± 0.25 | 34.6 ± 0.25 | 33.7 ± 0.25 | 20.1 ± 0.25 | 20.1 ± 0.25 | 34.8 ± 0.25 | 30.5 ± 0.25 | < 7 × 10−5 |
MiaPaca-2 | 30.3 ± 0.25 | 87.5 ± 0.25 | 46.4 ± 0.25 | 17.3 ± 0.25 | 16.8 ± 0.25 | 10.0 ± 0.25 | 18.5 ± 0.25 | 17.4 ± 0.25 | 64.9 ± 0.25 | < 7 × 10−5 |