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Table 1 IC50 of natural and semi-synthetics compounds from A. zygia against P. falciparum

From: Cytotoxycity and antiplasmodial activity of phenolic derivatives from Albizia zygia (DC.) J.F. Macbr. (Mimosaceae)

 

Compounds IC50 (SI) in μM

1

2

3

4

5

7

8

9

10

Chloroquine

P. falciparum

> 100

25.1 ± 0.25

19.0 ± 0.25

> 100

> 100

> 100

> 100

7.5 ± 0.25

6.8 ± 0.25

0.00296

(nd)

(3.49)

(1.22)

(nd)

(nd)

(nd)

(nd)

(3.03)

(9.57)

  1. SI = IC50 HepG2 cell/IC50 P. falciparum